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Genome Clinic

What is Genomic medicine?

ゲノムのある診察室 Center for Genomic Medicine
(Center Director / Specially Appointed Vice-president)
MIKI YOSHIO
三木 義男

Do you know how your body supports your daily life?

Our bodies are like a grand story woven together by threads called DNA, the blueprint of life within our cells.

The information read from this DNA is called the genome. It contains significant information related to our constitution, medical conditions, and the effectiveness of medicines. This is why “genomic medicine” is getting popular.

What exactly is genomic medicine?

Genomic information contains essential information related to our constitution, medical conditions, and the effects of medicines. Genomic medicine is an innovative medical approach that analyzes this "genome information" in detail to prevent, diagnose, and treat diseases. This makes it possible to accurately understand the patient's constitution and disease state and offer optimal treatment for each patient.

What are the merits of genomic medicine?

  • Providing optimal treatment for each individual
    Providing optimal treatment for each individual

    You can choose the most effective medicines and treatments according to your constitution and medical condition. This increases the effectiveness of treatment while minimizing the risk of side effects.

  • Early detection of disease
    Early detection of disease

    Knowing your genetic predisposition in advance allows you to detect diseases early and take appropriate preventive measures.
    It also holds promise for early detection of cancer and early detection of cancer recurrence.

  • Healthcare maintenance support
    Healthcare maintenance support

    By knowing your genomic information, you can obtain guidelines for developing healthier lifestyle habits.

Genomic medicine has great potential to make future medical care safer and more effective. At our “genome-based clinic”, we unravel the story of your genes and provide genomic medicine that is optimized for each individual.

Genomic medicine at our hospital

Our hospital is actively working to promote genomic medicine. We have established the following departments as medical departments that support genomic medicine.

Pediatrics

小児科
OZONO KEIICHI
大薗 恵一

There are approximately 7,000 rare and intractable diseases, many of which are caused by genetic abnormalities. These diseases are especially prevalent in childhood. Genome-based medicine plays a significant role in treating these conditions. Every year, the number of genetically diagnosable rare and intractable diseases is increasing. For more information about rare and intractable diseases, please consult the Intractable Disease Medical Promotion Center or the pediatrics department.

Breast Surgery

乳腺外科
NAKAUCHI CHIAKI
中内 千暁

As a breast surgeon, we mainly treat hereditary breast and ovarian cancer syndromes.
Please feel free to contact us if you have a family history of breast cancer, ovarian cancer, or pancreatic cancer.

Neurology

脳神経内科
ONISHI SHIZUO
大西 静生

Diseases of the brain (especially intractable neurological diseases), the most mysterious organ, are said to be closely related to genes (genomes). If you have a family history of neurological disease and are concerned about symptoms, please feel free to consult a neurologist.

Cardiovascular Medicine

循環器内科
TOYAMA YASUYUKI
外山 康之

In the area of cardiovascular disease, early diagnosis of familial hypercholesterolemia, which causes a high rate of myocardial infarction, hereditary arrhythmia, which can lead to sudden death, and hereditary cardiomyopathy is an essential requirement.
Additionally, people who take medications for prolonged periods for conditions such as high blood pressure or ischemic heart disease can also use drug-responsive genetic testing to check how well a drug works and how likely it is to cause side effects. Please feel free to contact us.

Digestive System Surgery

消化器外科
HINO HITOSHI
日野 仁嗣

Cancer is a disease caused by genetic abnormalities, and in gastrointestinal surgery, we primarily treat gastrointestinal cancers like stomach, colon, pancreatic, liver, and esophageal cancers.
Recent research has made it possible to predict the nature of cancer and the effectiveness of anticancer drugs by examining the details of genetic abnormalities in cancer. If you have any questions, please feel free to contact us.

Nephrology

腎臓内科
MORI YUKI
森 優希

In chronic kidney disease (CKD), renal function and genetic material in the urine protien are identified as relavant. In the future, research to recruit CKD risk factors and source genetic material is expected to accelerate. Even in polycystic kidney, the most frequent hereditary kidney disease, genome analysis has revealed factors involved in renal functional deterioration, and is expected to contribute to diagnostic treatment. In our department, we would like to respond sequentially according to the necessity.

Otorhinolaryngology

耳鼻咽喉科
SAKAMOTO HIROKAZU
阪本 浩一

My name is Sakamoto and I am an otorhinolaryngologist. I have been involved in genetic treatment for hearing loss since around 2008 when I was working at Hyogo Prefectural Children's Hospital. As a clinical geneticist, I am currently responsible for the genomic outpatient department at Osaka Public University, where I offer genomic treatment for conditions such as hearing loss and tumors. At our hospital, I also accept consultations for genetic diagnosis of hearing loss. If you have any concerns about genetics in the field of otorhinolaryngology, please feel free to contact us.

Dermatology

皮膚科
ISEI TAIKI
爲政 大幾

Since most skin cancers are rare cancers that occur in small numbers, there are currently very few treatments that are recommended with a high level of evidence when the cancer progresses.
In situations where the symptoms of skin cancer have advanced and traditional treatments are not available, or when approved medications covered by insurance have been proven unsuccessful, genome testing to identify potentially effective therapeutic drugs is considered a promising option. If you have such concerns, please consider consulting us regarding genome testing.

Urology

泌尿器科
KONO JUNKO
光野 絢子

In the urology department, Oraparib (product name: rim parser) was used to treat metastic castration resistant prostate cancer.
Various treatments are covered by various treatments for castration resistant prostate cancer, but Oraparib can only be used when BRCA gene abnormalities are observed.
Please feel free to contact us.

SOPHIA Complete Medical Checkup Center

人間ドックSOPHIA
ANDO KOSHIRO
安藤 紘史郎

SOPHIA has conducted comprehensive genome diagnoses, including cancer genome checkups, since 2023.
We are also developing several other tests that involve genome analysis.
We have entered an era where discussions about medical examinations must inherently include considerations of the genome. Feel free to reach out to us for more information!

Obstetrics
産科
Gynecology
婦人科

For those interested in genomic medicine

If you are interested in genomic medicine, please feel free to contact any of our hospital departments.

Genome Clinic